Biostimulatory Molecules in NYC | Sculptra® and Hyperdilute Radiesse®
Biostimulatory injectables are an advanced, non-surgical way to restore volume, tighten skin, and improve texture. At Park Ave. Derm, we offer two powerful options, Sculptra® and Hyperdilute Radiesse®, to stimulate natural collagen production for long-lasting facial rejuvenation.
These treatments do more than temporarily fill lines. They activate your skin’s natural ability to rebuild firmness and elasticity over time. Whether you are looking to address early volume loss, sagging, or skin thinning in the face, neck, chest, or body, our dermatologists at Park Ave. Derm will customize a treatment plan based on your individual needs.
What Are Biostimulatory Injectables?
Sculptra® (poly-L-lactic acid) and Hyperdilute Radiesse® (calcium hydroxylapatite) are classified as biostimulatory injectables. Rather than simply filling wrinkles or folds, these products work by encouraging your body to produce more collagen in the treated areas.
Over time, collagen stimulation leads to:
- Smoother, firmer skin
- Better texture and tone
- Restored facial volume
- Results build gradually and tend to last longer than traditional dermal fillers.
Sculptra®: Collagen Stimulation for the Face
Sculptra® is ideal for patients who want gradual, natural-looking improvements without the risk of looking overfilled. It is especially effective in areas with volume loss or skin laxity.
Common treatment areas include:
- Cheeks and temples
- Smile lines and marionette lines
- Jawline, chin, and neck
Key benefits of Sculptra®:
- Stimulates collagen production
- Improves skin quality and firmness
- Long-lasting results (up to 2.5 years)
- Builds volume subtly over time
A typical treatment plan includes 3 sessions spaced one month apart. Our dermatologists will adjust this timeline based on your goals and response to treatment.
Hyperdilute Radiesse®: Skin Tightening with Immediate Lift
Hyperdilute Radiesse® is a refined formulation of traditional Radiesse®, thinned with saline and lidocaine to allow for wide, even distribution in the skin. It works both as a collagen stimulator and a soft tissue support material, making it useful in areas where the skin is thin or crepey.
Common treatment areas include:
- Lower face, jawline, and neck
Key benefits of Hyperdilute Radiesse®:
- Immediate improvement in skin quality
- Visible firming and smoothing over time
- Stimulates collagen and elastin
- Minimal downtime
- Long-lasting (12+ months in most cases)
This injectable is especially helpful in areas where the skin has thinned due to aging, sun exposure, or weight loss.
Who Is a Good Candidate for Sculptra® and Hyperdilute Radiesse®?
Biostimulatory treatments are appropriate for a wide range of patients seeking subtle but significant rejuvenation. Ideal candidates typically show:
- Volume loss in the face
- Skin laxity or crepey skin
- Fine lines and wrinkles
- Visible collagen decline
- Clinical evidence of cosmetic concerns
During your consultation, the dermatologists at Park Ave. Derm will determine whether Sculptra®, Hyperdilute Radiesse®, or a combination of both is appropriate for your skin and aesthetic goals.
What to Expect During Treatment
- Both Sculptra® and Hyperdilute Radiesse® injections are performed in-office and typically take 30 to 45 minutes.
- Your dermatologist will cleanse the area and may apply topical numbing.
- A fine needle or cannula is used to inject the product into precise anatomical planes.
- You may experience mild swelling or bruising after treatment, which resolves within a few days.
- Unlike traditional fillers, these treatments do not provide immediate final results. Full improvement unfolds gradually over several weeks to months.
How Long Do Results Last?
Sculptra® results can last up to 2.5 years, depending on your skincare regimen and sun avoidance techniques.
Hyperdilute Radiesse® typically lasts 12 to 18 months but may require maintenance based on the area treated.
Since both products stimulate your body’s own collagen production, results improve over time and appear natural.
Biostimulatory Treatments FAQs
Sculptra® and Hyperdilute Radiesse® promote your body’s collagen production, which strengthens the skin structure and adds volume over time. The result is firmer, smoother, and more youthful-looking skin.
Most patients experience only mild discomfort. A topical anesthetic or lidocaine dilution is used to minimize sensitivity.
Improvements begin gradually, with noticeable changes typically visible within 4 to 6 weeks. Full results may take several months.
Yes. Many patients choose to combine Sculptra® or Hyperdilute Radiesse® with Botox®, laser resurfacing, or PRP facial rejuvenation.
Side effects may include mild swelling, redness, or bruising at the injection site. Rarely, small nodules may form with Sculptra® if massage instructions are not followed. All risks and aftercare steps will be reviewed during your appointment.
Sculptra® is typically performed in a series of 2 to 3 sessions, while Hyperdilute Radiesse® may require one to two sessions depending on the area treated and your goals.
No. Hyperdilute Radiesse® can benefit adults of many ages, especially those noticing early signs of collagen loss, crepey skin, or thinning in areas like the neck, chest, or arms.
Sculptra® uses poly-L-lactic acid to stimulate collagen deep in the dermis, while Hyperdilute Radiesse® uses calcium-based microspheres in a gel carrier. Sculptra® tends to be better for volume restoration, while Radiesse® excels at improving skin tone, firmness, and elasticity.
Yes. After Sculptra® treatment, you will be instructed to massage the treated areas for 5 minutes, 5 times a day, for 5 days. This helps distribute the product evenly and reduces the risk of nodules.
Both treatments have minimal downtime. Most patients return to normal activities the same day. Mild swelling or bruising can occur but typically resolves within a few days.
No. Sculptra® and Hyperdilute Radiesse® are not recommended during pregnancy or breastfeeding due to the lack of safety data in these populations.
Follow-up sessions every 12 to 24 months are typically recommended, depending on the product used, the treatment area, and how your skin responds. Ongoing collagen stimulation helps preserve the aesthetic improvements.
Schedule Your Biostimulatory Injectable Appointment
If you would like to schedule your biostimulatory injectable treatment with Sculptra® or Hyperdilute Radiesse®, please fill out our contact form or call us at (212) 752-3692. We will do our very best to provide you with an appointment in a timely manner.
